A hypothesis: Fructosamine-3-Kinase-Related-Protein (FN3KRP) catalyzes deglycation of Maillard intermediates directly downstream from fructosamines

Non-enzymatic glycation (a.k.a. Maillard reaction) is a series of random spontaneous reactions between reducing sugars and amines resulting in the formation of irreversible Advanced Glycation Endproducts (AGE’s). In food chemistry, this process is beneficial by contributing to flavor, aroma, texture and appearance of cooked foods. In vivo, however, Maillard reaction is deleterious because uncontrolled modification…

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Ultra Pure Gel

National Diagnostics Partner PROTOGEL

Catalog quantity: EC-890 Nationwide Diagnostics ProtoGel kinds an electrophoresis matrix that’s perfect for the separation of proteins and polypeptides. ProtoGel is a stabilized, ready-to-use 30% (w/v) acrylamide/methylene bisacrylamide resolution (37.5:1 ratio) manufactured from the very best high quality supplies from which nearly all impurities have been eliminated. ProtoGel has zero acrylic acid content material, eliminating the…

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Spherotech

SPHEROTM Silica Particles – Spherotech

Merchandise Superparamagnetic Particles Quick isolation of viable and functionally lively cells utilizing magnetic labeling after coupling with cell floor molecules Accessible with quite a lot of floor chemistries for secure binding and optimum orientation of biomolecules Develops a robust inner magnetization when uncovered to an exterior magnetic subject Don’t retain any web magnetization as soon…

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arborassays

Arbor Assays | ELISA Kits, Detection Assays, & more

Arbor Assays is to construct the best high quality detection and immunoassay merchandise for clinically essential biomolecules. We construct strong immunoassay and enzyme exercise kits to quantitate biomolecules in organic matrices. The founders and high scientists from Arbor Assays have been researching and growing prime quality assay kits since 1982. We grew up making FDA-regulated…

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Concavalin A

Concanavalin A Hepatitis

Concanavalin A (Con A) is a plant lectin that’s purified from jack beans. Con A binds to the mannose residues of assorted glycoproteins and prompts lymphocytes. When Con A is run to mice, liver damage that will depend on the activation of T lymphocytes by macrophages happens (Tiegs et al., 1992). Due to this fact, the mannequin may enable the examine of the pathophysiology of immunologically mediated…

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