immpact-international

First-Line Therapy for Chronic Lymphocytic Leukemia: Bruton Tyrosine Kinase or BCL2 or Both?

Novel therapies largely have changed chemoimmunotherapy as optimum first-line therapy of persistent lymphocytic leukemia (CLL). Accredited novel therapies for CLL within the first-line setting embody Bruton tyrosine kinase inhibitors, ibrutinib and acalabrutinib, and the BCL2 inhibitor venetoclax. Every of those novel brokers has its personal distinctive attributes they usually haven’t been in contrast face to face in randomized trials. This overview summarizes the pivotal trials that led to the approval of novel brokers and compares the options of every agent to information therapy choices in treatment-naïve CLL. Ongoing research investigating combos of novel brokers within the first-line setting are also mentioned.

Community-based techniques pharmacology reveals heterogeneity in LCK and BCL2 signaling and therapeutic sensitivity of T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy, and novel therapeutics are a lot wanted. Profiling affected person leukemia’ drug sensitivities ex vivo, we found that 44.4% of childhood and 16.7% of grownup T-ALL circumstances exquisitely reply to dasatinib. Making use of network-based techniques pharmacology analyses to look at sign circuitry, we recognized preTCR-LCK activation as the driving force of dasatinib sensitivity, and T-ALL-specific LCK dependency was confirmed in genome-wide CRISPR-Cas9 screens.
Dasatinib-sensitive T-ALLs exhibited excessive BCL-XL and low BCL2 exercise and venetoclax resistance. Discordant sensitivity of T-ALL to dasatinib and venetoclax is strongly correlated with T-cell differentiation, notably with the dynamic shift in LCK vs. BCL2 activation. Lastly, single-cell evaluation recognized leukemia heterogeneity in LCK and BCL2 signaling and T-cell maturation stage, in step with dasatinib response. In conclusion, our outcomes point out that developmental arrest in T-ALL drives differential activation of preTCR-LCK and BCL2 signaling on this leukemia, offering distinctive alternatives for focused remedy.

Blood concentrations of proapoptotic sFas and antiapoptotic Bcl2 and COVID-19 affected person mortality

Background: Cell dying by apoptosis is elevated in septic sufferers. Nonetheless, there are usually not information about circulating concentrations of sFas (proapoptotic protein of extrinsic pathway) and Bcl2 (antiapoptotic protein of intrinsic pathway) in COVID-19 sufferers. Thus, our goal examine was to find out whether or not exists an affiliation between serum concentrations of sFas and Bcl2 and COVID-19 affected person mortality.
Strategies: This observational and potential examine of COVID-19 sufferers was carried out in eight Intensive Care Items (ICU) from Canary Islands (Spain). Serum ranges of sFas and Bcl2 at ICU admission had been decided. Mortality at 30 days was the end-point examine.
Outcomes: Surviving sufferers (n=42) in comparison with non-surviving (n=11) had decrease APACHE-II (p<0.001), decrease SOFA (p=0.004), decrease serum sFas ranges (p=0.001) and better serum Bcl2 ranges (p<0.001). Logistic regression confirmed an affiliation between excessive serum sFas ranges and mortality after controlling for APACHE-II (OR=1.004; 95% CI=1.101-1.007; p=0.01) or SOFA (OR=1.003; 95% CI=1.101-1.106; p=0.004), and between low serum Bcl2 ranges and mortality after controlling for APACHE-II (OR=0.927; 95% CI=0.873-0.984; p=0.01) or SOFA (OR=0.949; 95% CI=0.913-0.987; p=0.01).
Conclusions: Thus, to the most effective of our data, that is the primary examine reporting blood ranges of sFas and Bcl2 in COVID-19 sufferers and its affiliation with mortality.
Key phrases: Bcl2; COVID-19: sufferers; mortality; sFas.
immpact-international
immpact-international

Galectin-Three immunolabelling correlates with BCL2 expression in canine cutaneous mast cell tumours

Mast cell tumour (MCT) is essentially the most frequent pores and skin neoplasm in canine. These tumours are characterised by variable behaviour and scientific presentation that make prognosis an essential and difficult process within the veterinary follow. Galectin-3 (Gal-3) is thought to affect a number of organic processes which are essential within the most cancers context and has been described as a prognostic marker for a number of human cancers.
  • The goal of the current work was to characterise Gal-Three immunolabelling in canine cutaneous MCTs and to research its worth as a prognostic marker for the illness. Thirty-four random circumstances of canine cutaneous MCT that had been surgically handled with broad margins had been included on this examine. Gal-Three expression was evaluated utilizing immunohistochemistry and the outcomes had been in contrast with the expression of apoptosis-related proteins, Ki67 index, histopathological grades, mortality as a result of illness and post-surgical survival.
  • Nearly all of the MCTs (65.8%) had been constructive for Gal-3. Gal-Three immunolabelling was variable among the many samples (2.7%-86.8% of the neoplastic cells). The protein was situated within the cytoplasm or within the cytoplasm and the nucleus. Gal-Three positivity was correlated with BCL2 expression (P < 0.001; r = 0.604), however not with Ki67 and BAX. No vital variations had been detected between histological grades or within the survival evaluation.
  • Gal-Three expression correlates with BCL2 expression in MCTs. Though an environment friendly marker for a number of human neoplasms, the outcomes offered herein counsel that Gal-Three immunolabelling just isn’t an impartial prognostic indicator for this illness.

Silica Nanoparticles Induce Hepatotoxicity by Triggering Oxidative Injury, Apoptosis, and Bax-Bcl2 Signaling Pathway

The rise within the utilization of silica nanoparticles (SiNPs) within the industrial and medical fields has raised considerations about their doable opposed results on human well being. The current examine aimed to research the potential opposed results of SiNPs at day by day doses of 25 and 100 mg/kg physique weight intraperitoneally (i.p.) for 28 consecutive days on markers of liver harm in grownup male rats. Outcomes revealed that SiNPs induced a marked enhance in serum markers of liver harm, together with lactate dehydrogenase (LDH), alanine aminotransferase (ALAT), and aspartate aminotransferase (ASAT).
SiNPs additionally induced an elevation of reactive oxygen species (ROS) manufacturing in liver, together with a rise in oxidative stress markers (NO, MDA, PCO, and H2O2), and a lower in antioxidant enzyme actions (CAT, SOD, and GPx). Quantitative real-time PCR confirmed that SiNPs additionally induced upregulation of pro-apoptotic gene expression (together with Bax, p53, Caspase-9/3) and downregulation of anti-apoptotic elements Bcl-2.
Furthermore, histopathological evaluation revealed that SiNPs induced hepatocyte alterations, which was accompanied by sinusoidal dilatation, Kupffer cell hyperplasia, and the presence of inflammatory cells within the liver. Taken collectively, these information confirmed that SiNPs set off hepatic harm by ROS-activated caspase signaling pathway, which performs a basic function in SiNP-induced apoptosis within the liver.

Mouse Bcl 2 like protein 11(BCL2L11) ELISA kit

E03B0766-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Bcl 2 like protein 11(BCL2L11) ELISA kit

E03B0766-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Bcl 2 like protein 11(BCL2L11) ELISA kit

E03B0766-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Bcl- 2- like protein 11, Bcl2l11 ELISA KIT

ELI-24063m 96 Tests
EUR 1038

Recombinant Human Bcl-2-like Protein 11/BIML (N-6His)

CR24-10ug 10ug
EUR 242.4
Description: Supplied as a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, 10% glycerol, 2mM DTT, pH8.0

Recombinant Human Bcl-2-like Protein 11/BIML (N-6His)

CR24-1mg 1mg
EUR 2983.2
Description: Supplied as a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, 10% glycerol, 2mM DTT, pH8.0

Recombinant Human Bcl-2-like Protein 11/BIML (N-6His)

CR24-500ug 500ug
EUR 1935.6
Description: Supplied as a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, 10% glycerol, 2mM DTT, pH8.0

Recombinant Human Bcl-2-like Protein 11/BIML (N-6His)

CR24-50ug 50ug
EUR 595.2
Description: Supplied as a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, 10% glycerol, 2mM DTT, pH8.0

Recombinant Human Bcl-2-like protein 11 Protein, His, Yeast-100ug

QP5712-ye-100ug 100ug
EUR 576

Recombinant Human Bcl-2-like protein 11 Protein, His, Yeast-10ug

QP5712-ye-10ug 10ug
EUR 283.2

Recombinant Human Bcl-2-like protein 11 Protein, His, Yeast-1mg

QP5712-ye-1mg 1mg
EUR 2262

Recombinant Human Bcl-2-like protein 11 Protein, His, Yeast-200ug

QP5712-ye-200ug 200ug
EUR 892.8

Recombinant Human Bcl-2-like protein 11 Protein, His, Yeast-500ug

QP5712-ye-500ug 500ug
EUR 1447.2

Recombinant Human Bcl-2-like protein 11 Protein, His, Yeast-50ug

QP5712-ye-50ug 50ug
EUR 358.8

Human Bcl 2 like protein 11(BCL2L11) ELISA kit

E01B0766-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Bcl 2 like protein 11(BCL2L11) ELISA kit

E01B0766-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Bcl 2 like protein 11(BCL2L11) ELISA kit

E01B0766-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Bcl-2-like protein 11(BCL2L11) ELISA kit

CSB-EL002615HU-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human Bcl-2-like protein 11 (BCL2L11) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Bcl-2-like protein 11(BCL2L11) ELISA kit

1-CSB-EL002615HU
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Bcl-2-like protein 11(BCL2L11) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Bcl 2 like protein 11(BCL2L11) ELISA kit

E02B0766-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Bcl 2 like protein 11(BCL2L11) ELISA kit

E02B0766-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Bcl 2 like protein 11(BCL2L11) ELISA kit

E02B0766-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Bcl 2 like protein 11(BCL2L11) ELISA kit

E07B0766-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Bcl 2 like protein 11(BCL2L11) ELISA kit

E07B0766-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Bcl 2 like protein 11(BCL2L11) ELISA kit

E07B0766-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Bcl 2 like protein 11(BCL2L11) ELISA kit

E06B0766-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Bcl 2 like protein 11(BCL2L11) ELISA kit

E06B0766-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Bcl 2 like protein 11(BCL2L11) ELISA kit

E06B0766-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Bcl 2 like protein 11(BCL2L11) ELISA kit

E08B0766-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Bcl 2 like protein 11(BCL2L11) ELISA kit

E08B0766-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Bcl 2 like protein 11(BCL2L11) ELISA kit

E08B0766-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Bcl 2 like protein 11(BCL2L11) ELISA kit

E09B0766-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Bcl 2 like protein 11(BCL2L11) ELISA kit

E09B0766-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Bcl 2 like protein 11(BCL2L11) ELISA kit

E09B0766-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Bcl 2 like protein 11(BCL2L11) ELISA kit

E04B0766-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Bcl 2 like protein 11(BCL2L11) ELISA kit

E04B0766-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Bcl 2 like protein 11(BCL2L11) ELISA kit

E04B0766-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Bcl2L11(Bcl-2 Like Protein 11) ELISA Kit

EH2699 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

Human Bcl-2 Like Protein 11 (Bcl2L11) CLIA Kit

abx196479-96tests 96 tests
EUR 990

Human Bcl- 2- like protein 11, BCL2L11 ELISA KIT

ELI-34221h 96 Tests
EUR 988.8

Recombinant Human Bcl-2-like protein 11 Protein, His-SUMO, E.coli-100ug

QP5712-ec-100ug 100ug
EUR 489.6

Recombinant Human Bcl-2-like protein 11 Protein, His-SUMO, E.coli-10ug

QP5712-ec-10ug 10ug
EUR 240

Recombinant Human Bcl-2-like protein 11 Protein, His-SUMO, E.coli-1mg

QP5712-ec-1mg 1mg
EUR 1958.4

Recombinant Human Bcl-2-like protein 11 Protein, His-SUMO, E.coli-200ug

QP5712-ec-200ug 200ug
EUR 760.8

Recombinant Human Bcl-2-like protein 11 Protein, His-SUMO, E.coli-500ug

QP5712-ec-500ug 500ug
EUR 1272

Recombinant Human Bcl-2-like protein 11 Protein, His-SUMO, E.coli-50ug

QP5712-ec-50ug 50ug
EUR 315.6

ELISA kit for Human Bcl2L11 (Bcl-2 Like Protein 11)

E-EL-H0582 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Human Bcl2L11 (Bcl-2 Like Protein 11) in samples from Serum, Plasma, Cell supernatant

Guinea pig Bcl 2 like protein 11(BCL2L11) ELISA kit

E05B0766-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Bcl 2 like protein 11(BCL2L11) ELISA kit

E05B0766-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Bcl 2 like protein 11(BCL2L11) ELISA kit

E05B0766-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig Bcl 2 like protein 11(BCL2L11) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

CLIA kit for Human Bcl2L11 (Bcl-2 Like Protein 11)

E-CL-H0450 1 plate of 96 wells
EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Human Bcl2L11 (Bcl-2 Like Protein 11) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Rat Bcl-2-like protein 11 (BIM)

KTE101123-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Rat Bcl-2-like protein 11 (BIM) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Bcl-2-like protein 11 (BIM)

KTE101123-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Rat Bcl-2-like protein 11 (BIM) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Bcl-2-like protein 11 (BIM)

KTE101123-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Rat Bcl-2-like protein 11 (BIM) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Anti-Bcl-2/BCL2 Antibody

A00040-2 100ug/vial
EUR 400.8

Recombinant Human IL-11 Protein

PROTP20809-2 10ug
EUR 380.4
Description: IL-11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury. Recombinant Human IL-11 is a 19.3 kDa protein consisting of 179 amino acid residues.

Recombinant Human GDF-11 Protein

PROTO95390-2 20ug
EUR 380.4
Description: GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves arrest of progenitor cell-cycle in the G1 phase. Similarities between myostatin and GDF-11, which are 90% identical in their amino acid sequence, suggests that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same. Recombinant human GDF-11 is a 25.0 kDa disulfide-linked homodimer containing two 109 amino acid polypeptide chains. It is highly homologous to myostatin/GDF-8 sharing 90% amino-acid sequence identity.

Anti-Bcl-2 Rabbit Monoclonal Antibody

M00040-2 100ug/vial
EUR 476.4
Description: Rabbit Monoclonal Bcl-2 Antibody. Validated in IF, WB and tested in Human, Mouse.

Mouse Bcl 2 like protein 2(BCL2L2) ELISA kit

E03B0769-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Bcl 2 like protein 2(BCL2L2) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Bcl 2 like protein 2(BCL2L2) ELISA kit

E03B0769-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Bcl 2 like protein 2(BCL2L2) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Bcl 2 like protein 2(BCL2L2) ELISA kit

E03B0769-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Bcl 2 like protein 2(BCL2L2) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Bcl- 2- like protein 2, Bcl2l2 ELISA KIT

ELI-11430m 96 Tests
EUR 1038

Human Bcl-2-like protein 2 (BCL2L2)

1-CSB-EP821707HU
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Bcl-2-like protein 2(BCL2L2) expressed in E.coli

Bcl-2-Like Protein 2 (BCL2L2) Antibody

20-abx109264
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Bcl-2-like protein 12 antibody

22281-100ul 100ul
EUR 468

GFR alpha-like Recombinant Protein

11-410 0.1 mg
EUR 714.3
Description: GFR alpha-like is also known as GDNF family receptor alpha-like, GFRAL, C6orf144, UNQ9356, PRO34128. Growth differentiation factor-15 (GDF15) is a circulating protein that has been implicated in multiple biological processes, including energy homeostasis, body weight regulation, and cachexia driven by cancer and chronic disease. GDNF family receptor α-like (GFRAL) was recently identified as the neuronal brainstem receptor responsible for mediating the anorectic actions of GDF15. Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses . Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.

Human Bcl-2-like Protein 2 (BCL2L2) Antibody

32113-05111 150 ug
EUR 313.2

Mouse Bcl 2 like protein 1(BCL2L1) ELISA kit

E03B0764-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Bcl 2 like protein 1(BCL2L1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Bcl 2 like protein 1(BCL2L1) ELISA kit

E03B0764-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Bcl 2 like protein 1(BCL2L1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Bcl 2 like protein 1(BCL2L1) ELISA kit

E03B0764-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Bcl 2 like protein 1(BCL2L1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Bcl 2 like protein 10(BCL2L10) ELISA kit

E03B0765-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Bcl 2 like protein 10(BCL2L10) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Bcl 2 like protein 10(BCL2L10) ELISA kit

E03B0765-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Bcl 2 like protein 10(BCL2L10) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Bcl 2 like protein 10(BCL2L10) ELISA kit

E03B0765-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Bcl 2 like protein 10(BCL2L10) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Bcl 2 like protein 13(BCL2L13) ELISA kit

E03B0767-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Bcl 2 like protein 13(BCL2L13) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Bcl 2 like protein 13(BCL2L13) ELISA kit

E03B0767-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Bcl 2 like protein 13(BCL2L13) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Bcl 2 like protein 13(BCL2L13) ELISA kit

E03B0767-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Bcl 2 like protein 13(BCL2L13) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Bcl 2 like protein 15(BCL2L15) ELISA kit

E03B0768-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Bcl 2 like protein 15(BCL2L15) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.