Direct Detection of Feline Coronavirus by Three Rapid Antigen Immunochromatographic Tests and by Real-Time PCR in Cat Shelters

The aim of this study was the direct detection of feline coronavirus by real-time PCR and by three different rapid immunochromatographic (RIM) tests detecting antigens in faecal samples of shelter cats. Based on sensitivity and specificity calculated for each of the RIM tests, the utility of RIM tests was compared. Seventy faecal samples originating from…

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Selective killing of human M1 macrophages by Smac mimetics alone and M2 macrophages by Smac mimetics and caspase inhibition

Selective killing of human M1 macrophages by Smac mimetics alone and M2 macrophages by Smac mimetics and caspase inhibition

The inflammatory and anti inflammatory Mϕs have been implicated in lots of ailments together with rheumatoid arthritis, a number of sclerosis, and leprosy. Current research recommend focusing on Mϕ operate and activation could symbolize a possible goal to deal with these ailments. Herein, we investigated the impact of second mitochondria-derived activator of caspases (SMAC) mimetics…

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