Comparison of immunomagnetic beads coated with protein A, protein G, or goat anti-mouse immunoglobulins. Applications in enzyme immunoassays and immunomagnetic separations.
Immunomagnetic beads were prepared using either protein A (PA) or protein G (PG) coupled to magnetic beads for binding antibodies at their Fc region. The performance of these beads was compared with commercially available beads coated with goat anti-mouse (G alpha M) immunoglobulins. Both the PA- and PG-beads possessed a higher binding capacity than the…Read More
Proseek single-plex protein assay kit system to detect sAxl and Gas6 in serological material of brain tumor patients
The receptor tyrosine kinase (RTK) Axl and its ligand Gas6 are critically involved in the pathogenesis of high-grade glioma (HGG). Both proteins were found to be overexpressed e.g. in tumor cells, mediating cell proliferation and migration as well as tumor angiogenesis and neuroinflammation. The extracellular domain of Axl (sAxl) and Gas6 were found in the…Read More
Cardiotonic steroids are pure compounds that current many physiological and pharmacological capabilities. They bind Na+/Ok+-ATPase (NKA) modifying mobile ion focus and set off cell signaling mechanisms with out altering ion stability. These steroids are recognized to modulate some immune responses, together with cytokine manufacturing, neutrophil migration, and irritation (peripherally and within the nervous system). Irritation…Read More