Real-time in situ monitoring of Lon and Caspase-3 for assessing the state of cardiomyocytes under hypoxic conditions via a novel Au-Se fluorescent nanoprobe

Real-time in situ monitoring of Lon and Caspase-3 for assessing the state of cardiomyocytes under hypoxic conditions via a novel Au-Se fluorescent nanoprobe

Myocardial dysfunction attributable to cardiomyocyte apoptosis beneath ischemic and hypoxic situations is the pathological foundation of most cardiovascular illnesses. Present prognosis of myocardial dysfunction nonetheless focuses on the symptomatic stage, often after the prevalence of the irreversible remodelling and purposeful impairment. Thus, early stage identification of the apoptotic cardiomyocytes induced by hypoxia is very important…

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