Tag: rna-seq
Fe(III)-Shikonin Supramolecular Nanomedicine for Combined Therapy of Tumor via Ferroptosis and Necroptosis
A lot of the antitumor chemotherapeutic medication execute the therapeutic efficiency upon eliciting tumor cell apoptosis, which can trigger chemoresistance of tumors. Design of novel medication to eradicate apoptosis-resistant tumors through non-apoptotic cell dying pathways is promising for bettering the long-term chemotherapeutic efficacy. Herein, a Fe(III)-Shikonin metal-polyphenol-coordinated supramolecular nanomedicine for mixed remedy of tumor through…
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Real-time in situ monitoring of Lon and Caspase-3 for assessing the state of cardiomyocytes under hypoxic conditions via a novel Au-Se fluorescent nanoprobe
Myocardial dysfunction attributable to cardiomyocyte apoptosis beneath ischemic and hypoxic situations is the pathological foundation of most cardiovascular illnesses. Present prognosis of myocardial dysfunction nonetheless focuses on the symptomatic stage, often after the prevalence of the irreversible remodelling and purposeful impairment. Thus, early stage identification of the apoptotic cardiomyocytes induced by hypoxia is very important…
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