Precursor B-Cell Acute Lymphoblastic Leukemia With MYC and BCL2 Rearrangements Presenting as Extensive Extranodal Disease in an Adolescent

Mixed rearrangements of MYC and BCL2 are uncommon in precursor B-cell acute lymphoblastic leukemia (B-ALL). A 14-year-old boy offered with swelling of the knee and face. Imaging revealed diffuse infiltration of lacrimal glands, parotid glands together with the in depth epidural illness. Morphology and immunophenotype of knee joint aspirate have been in keeping with precursor…

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